ELECTROPULSES INDUCED DIRECT AGING AND ULTRAFAST PRECIPITATION IN ADDITIVE MANUFACTURED 15-5 PH STAINLESS STEEL

Electropulses induced direct aging and ultrafast precipitation in additive manufactured 15-5 PH stainless steel

Periodic electric current pulses, i.e.electropulses, were applied on selective laser DAMIANA melting prepared 15-5 precipitation hardening stainless steel for direct aging.Traditional aging treatment typically takes hours to achieve peak hardening and could induce reverted austenite.Herein, electropulsing treatment on as-built sample can dramatical

read more

Probing molecular mechanisms of the Hsp90 chaperone: biophysical modeling identifies key regulators of functional dynamics.

Deciphering functional mechanisms of the Hsp90 chaperone machinery is an important objective in cancer biology aiming to facilitate discovery of targeted anti-cancer therapies.Despite significant advances in understanding structure and function of molecular chaperones, organizing molecular principles that control the relationship between conformati

read more

Altered Glycosylation in the Aging Heart

Cardiovascular disease is one of the leading causes of death in developed countries.Because the incidence increases exponentially in the aging population, aging is a major risk factor for cardiovascular disease.Cardiac hypertrophy, fibrosis and inflammation are typical hallmarks of the aged heart.The molecular mechanisms, however, are poorly unders

read more